A8351
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A8351
Sigma
Ampicillin sodium salt
Biotechnology Performance Certified
| Synonym: | |
| CAS Number: | 69-52-3 |
| Linear Formula: | C16H18N3NaO4S |
| Molecular Weight: | 371.39 |
| Beilstein Registry Number: | 4119211 |
| EC Number: | 200-708-1 |
| MDL number: | MFCD00064313 |
| PubChem Substance ID: | 24891335 |
Description
| Biochem/physiol Actions | A β-lactam antibiotic with an amino group side chain attached to the penicillin structure. Penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli . Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria. |
Properties
| grade | Biotechnology Performance Certified |
| total impurities | Endotoxin, tested |
| mp | 215 °C (dec.)(lit.) |
| suitability | cell culture tested |
| storage temp. | 2-8°C |
Safety
| Personal Protective Equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 42/43 |
| Safety Statements | 22-36/37-45 |
| WGK Germany | 2 |
| RTECS | XH8400000 |
References
| reference | Raleigh, E.A., Ausubel, M., et al. Short Protocols in Molecular Biology 2nd ed., New York, NY , (1992) 12, 2 |
| Perlman, D., et al., Use of antibotics in cell culture. Meth. Enzymol. LVIII, 112, (1979) | |
| Merck | Merck 13,591 |
| Corp MSDS 1 (1), 247:C / RegBook 1 (2), 2065:J / Sax 6, 2410 / Sigma FT-IR 1 (1), 619:B / Structure Index 1, 328:C:3 |
